A BRIEF VIEW ON ANTIHYPERTENSIVE DRUGS DELIVERY THROUGH TRANSDERMAL PATCHESAbstract
Transdermal Drug Delivery System (TDDS) is one of the systems lying under the category of controlled drug delivery, in which the aim is to deliver the drug through skin in a predetermined and controlled rate. Hypertension is one of the common disorder for the mankind. It is not a disease in itself, but is an important risk factor for cardiovascular mortality and morbidity. The present article delivers a brief view on the work been done to increase the bioavailability of various antihypertensive drugs by formulated and delivered as transdermal patches. The different drugs includes carvedilol, metoprolol, atenolol, propranolol, labetolol, verapamil, indapamide, losartan, bisoprolol, timolol maleate, nicardipine hydrochloride, captopril, clonidine, pinacidil, nitrendipine, nicorandil, diltiazem hydrochloride, lisinopril, nifedipine, amlodipine, valsartan, enalapril maleate.