A BURDEN OF GASTROENTERITIS ASSOCIATED WITH COMORBIDITIES AN EFFECTIVE MANAGEMENT STRATEGYAbstract
Acute gastroenteritis prevalent amongst children and newborns is considered a serious infection globally. The Acute diarrhea as a result of gastroenteritis as per logistics suggest that there were more than 1.5 million outpatient visits along with 200,000 hospitalizations and 300 fatalities per year in children in U.S. Diarrhea is the leading cause of deaths amongst children with 30% relapse rate. The viral gastroenteritis caused by the Rotavirus is one the significant strain contributing the gastroenteritis. The suggestive therapies include Oral rehydration therapy (ORT) respective to age modulating the diet and ORS solutions. The gastroenteritis condition cannot be neglected but can be considered as significant public health issue especially in the elder patients with fatality ratio compared to children. The diagnosis of gastroenteritis includes signs, symptoms and stool cultures. The comorbidities in the patients when treated with variety of drugs is resulting damage of stomach lining and worsening the conditions of gastroenteritis. The comorbidities include the cardiovascular diseases, kidney related diseases and other infections playing major role for the chronic condition. There is need of clinical intervention for improvement of treatment, prevent reoccurrence and suggest the antibiotic rational use in the patients with comorbidities. The present review has represented the global data of infection causing agents, contributing factors of comorbidities leading to gastroenteritis, diagnosis and alternative treatment. The need of change in diet and rationale use of antibiotics is best measure to prevent the relapse of disease leading to less hospitalizations. The support from the alternative systems of medicine was suggested to improve the patient condition and also to prevent the reoccurrence.
Sneha Thakur *, Ayesha Unissa, Saleha Begum and Mahvish Fatima
Department of Pharmacognosy, St. Pauls College of Pharmacy, Sy. No. 603 & amp; 605, Hyderabad, Nagarjuna Sagar Rd, Turkayamjal, Telangana, India.
17 June 2022
14 August 2022
19 November 2022
01 February 2023