A COMPARATIVE STUDY OF DOT AND SAT IN RURAL TERTIARY CARE HOSPITAL: A TWO YEARS RETROSPECTIVE STUDYAbstract
Directly observed therapy (DOT) of tuberculosis patients talking their drugs is supposed to improve treatment completion and outcome .we compared DOT and Self Administered therapy (SAT), in which patients on the same drug regimen are not, observed taking their pills, to assess the effect of each on the success of tuberculosis treatment. This was the two year (2010 and 2011) retrospective study of tuberculosis patients admitted to the AH and RC.A total of 308 patients cases were analyzed. The majority of the cases were within 21-40 years TB patients were 38.96% of the total. Among the all TB patients with chronic illness others were 18(58.44%) more. Among 308 patients TB patients 131(42.53%) TB patients undergone DOT and 177 (57.46%) TB patient’s undergone SAT therapy. The comparative outcome between DOT and SAT were 110(86.61%) of cure and in SAT were 90 (57.32%). Only 5(03.93%) treatment failure, acquired drug resistance 01(00.78%), follow up lost were 11(08.66%) in DOT as compared to SAT 23(14.64%), 06(03.82%), 23(14.64%) respectively. There is no relapse and death in DOT therapy but in SAT therapy relapse were 10(06.36%) and deaths were 05(03.18%). There were large and significant difference in the cure, treatment failure, relapse and death rates between TB patient who receive DOT and SAT therapy respectively.