A COMPLETE RECAPITULATION OF A DRUG DELIVERY BASED ON OSMOTIC PRESSURE: AN OSMOTIC DRUG DELIVERY SYSTEMAbstract
Conventional dosage forms are the systems that don’t have complete control on their drug release, and also there is no control over the effective concentration at the target site. So in order to overcome this problem the osmotic drug delivery system was developed for the controlled delivery of drugs. This osmotic drug delivery system includes dosage forms for oral administration and implantable systems where they provide controlled delivery of drugs. These systems contain osmotic agents and a semipermeable membrane where they play an important role in the development of these delivery systems. This review mainly concentrates on the main Advantages, the principle of osmosis and how the drugs are delivered by using osmotic pressure, historical background, Types of osmotic drug delivery – Implantable and oral osmotic system, their pictorial representations and mechanisms, factors influencing the drug release, scientific developments and Marketed products of osmotic drug delivery systems.
Alla Monisha *, M. Mohan Varma, D. Basava Raju
Department of Formulation Research & Development, Aurigene Pharmaceutical Services (Subsidiary of Dr. Reddy’s Laboratories), CPS, Miyapur, Hyderabad, Telangana, India.
20 August 2020
22 June 2021
30 June 2021
01 October 2021