A COMPREHENSIVE INSIGHT INTO ARTIFICIAL BLOODAbstract
In hospitals, blood transfusions are a common occurrence. Because blood-related products are limited and have a range of adverse side effects, researchers have worked on artificial blood components for nearly 40 years. It is crucial to develop effective and selective alternatives for natural blood products. Artificial blood is a useful idea in transfusion medicine wherein clearly defined compounds perform the functions of oxygen transport and distribution in the body to enhance allogeneic human blood transfusion. Several molecules are created over a long period of time to achieve this goal, and ongoing modifications are performed in the pursuit of the ideal blood substitute. Currently, perfluorocarbons (PFC) or haemoglobin derived from outdated human/bovine blood (Hemoglobin Based Oxygen Carriers; HBOC) are used to manufacture artificial blood. The focus of this review paper is to provide a comprehensive view of different developed products that can be used as blood alternatives.
A. V. More *, S. Y. Sayyed, P. G. Morankar, S. R. Churi, S. S. Gawli, R. A. Karande and R. Y. Gorade
St. John Institute Of Pharmacy and Research, St. John Technical Campus, Palghar, Maharashtra, India.
22 June 2022
18 August 2022
30 August 2022
01 March 2023