A COMPREHENSIVE REVIEW OF XANTHENE AND THIOXANTHENE
AbstractXanthene (or 9H-xanthene) is a parent active compound in which a pyran ring is combined with a benzene ring on both sides, whereas in thioxanthene, the oxygen of xanthene is replaced by a sulphur atom. Xanthene and thioxanthene are important classes of organic compounds which exhibit diverse pharmacological activities such as anti-spasmodic, anti-parkinsonian, anti-psychotic, anti-rhinitic, anti-inflammatory, anti-asthmatic, anti-ulcer, etc. This review covers various methods of synthesis of Xanthene and Thioxanthene. The pharmacoeconomic consideration of various marketed products of Xanthene and Thioxanthene are also discussed. It also covers the ongoing clinical trials of the upcoming Xanthene and Thioxanthene-based products and the newer indication of existing drugs. This review would be of immense use to researchers interested in Xanthene and Thioxanthene-based drugs. This review also helps the physician to preferably prescribe the cheaper brand for the patient’s benefit with the help of pharmacoeconomic analysis discussed in the review.
Article Information
1
2550-2561
1369 KB
836
English
IJPSR
Darakhshan Parveen * and Amrita Parle
Department of Pharmaceutical Chemistry, Delhi Pharmaceutical Sciences and Research University, Mehrauli - Badarpur Rd, Sector 3, Pushp Vihar, New Delhi, New Delhi, India.
suhana.dk@gmail.com
26 May 2021
31 May 2022
02 June 2022
10.13040/IJPSR.0975-8232.13(7).2550-61
01 July 2022
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