A NOVEL APPROACH TO TREAT NEUROLOGICAL DISORDER BY USING LIPID-BASED DRUG DELIVERY SYSTEM
AbstractOne in every three people suffers from some kind of neurological disorder. Considering the huge burden of the disease, it is imperative to develop and treat such conditions. Because of time constraints and obstacles, treating neurological disorders remains challenging for medical professionals. The number of new pharmacologically active lipid compounds discovered using current drug development methods is steadily growing, but these compounds are water-insoluble. Having a drug for oral administration with optimal bioavailability was a huge risk. Epilepsy is a serious medical condition that requires immediate treatment. We need to make lipid-based formulations to improve their bioavailability. Surface tension-lowering agents can result in a water-insoluble formulation. Niosomes and nanoparticles will pass freely along the blood-brain barrier. The key goals in the development of nanomedicine are safety, high therapeutic effectiveness, drug targeting to specific locations to avoid off-target toxicity and increased pharmacokinetic behaviour through prolonged drug release with a significant safety margin. As a result, the highest clinical effectiveness can be reached by combining lipid and protein therapies.
Article Information
4
2222-2229
567 KB
294
English
IJPSR
Pooja Agarwal * and Vasudha Bakshi
School of Pharmacy, Anurag University, Venkatapur, Ghatkesar, Medchal District, Hyderabad, Telangana, India.
pharmacy.pooja.agarwal@gmail.com
24 August 2023
14 June 2024
06 July 2024
10.13040/IJPSR.0975-8232.15(7).2222-29
01 August 2024