A PHYTO PHARMACOLOGICAL REVIEW ON TRADITIONAL MEDICINAL PLANT ZIZIPHUS RUGOSA LAM
AbstractZiziphus rugosea member of Rhamnaceae family, is found in the deciduous and semi-evergreen forests of Western Ghats, India. It is commonly known as suran in Hindi. chunukoli in Urdu, badara in Sanskrit, and toran in Marathi. Z. rugosa is traditionally used in the treatment of skin diseases, mouth ulcers, dropsy, boils, diarrhea, tachycardia, syphilis, miscarriage, misconception, flatulence, hysteria, And as astringent. It has been investigated foranti-diabetic, anti-inflammatory, α-glucosidase inhibitory, cytotoxic, antioxidant, antibacterial, anthelmintic, analgesic, and insecticidal activities. It is reported to contain diverse classes of secondary metabolites like alkaloids, flavonoids, glycosides, saponins, triterpenoids, tannins and phenolics. Several constituents are reported from different parts of this plant cyclopeptide alkaloids (rugosanin-A, amphibine-D, rugosanin-B, sativanin-H, nummularine-P), pentacyclic triterpenoids (2-α-hydroxyursolic acid, oleanalic acid, alphitolic acid, betulinaldehyde, betulin, betulinic acid, lupeol), flavonoids (kaempferol, quercetin, myricetin, apigenin, apigenin-7-o-glucoside, kaempferol-4-methylether, kaempferol-3-o-rhamnoside, luteolin, luteolin -7-o-glucoside), dihydroxy benzoic acid (vanilic acid), quinoline (isoquinoline). The present review is an attempt to connect the traditional use of Z. rugosa to its phytochemistry and pharmacology, thereby opening up new avenues in the therapeutic utility of this traditional medicinal plant.
Article Information
4
1456-1462
910 KB
567
English
IJPSR
Sushma Gaikwad and Tabassum Khan *
Department of Pharmaceutical Chemistry and Quality Assurance, SVKM’s, Dr. Bhanuben Nanavati College of Pharmacy, Mithibai Campus, Vile Parle (West), Maharashtra, India.
tabassum.khan@bncp.ac.in
27 May 2021
14 August 2021
16 August 2021
10.13040/IJPSR.0975-8232.13(4).1456-62
01 April 2022