A PRELIMINARY EVALUATION OF ANTIBACTERIAL AND TOXIC POTENTIALS OF P. GUINEENSE SWARTZ. FRUIT PULP FROM DIFFERENT STAGES OF RIPENESSAbstract
Psidium guineense Swartz is a shrub native to Brazil. It is consumed in natura or in the form of pulp, which presents a high content of C vitamin and proteins. The chemical prospection of the aqueous extracts from unripe and mature pulp revealed the presence of tannins and flavonoids. The extracts demonstrated moderate antibacterial activity against the most of strains tested, and the best result was obtained with the unripe pulp extract against Staphylococcus aureus (MR358; MIC 256 μg/mL). The extracts were further tested for in vivo brine shrimp lethality test. The mature pulp extract exhibited significant toxicity (LC50=125 μg/mL).
Samara Alves Brito , Fabiola Fernandes Galvao Rodrigues , Adriana Rolim Campos , Jose Galberto Martins da Costa*
Molecular Bioprospection Post-graduation Program, Laboratory of Natural Products Research, Regional University of Cariri, Crato, CE, Brazil
04 August, 2010
14 November, 2010
24 December, 2010