A PROSPECTIVE OBSERVATIONAL STUDY ON ADVERSE DRUG REACTION AMONG PATIENTS IN A TERTIARY CARE HOSPITALAbstract
Adverse drug reactions (ADRs) cause considerable morbidity and mortality worldwide. The pharmacovigilance activities continuously update about the adverse reactions related to medications and provide information regarding the nature and severity of ADRs. The study aims to assess the causality assessment of ADRs among patients in a tertiary care hospital. A prospective observational study was conducted in a tertiary care hospital for eight months, from September 2019 to April 2020. A total of 87 patients among 79 patients had reported with 82 ADRs. Based on the gender, males were higher than females. 40 ADRs were reported between 61-80 years of age. 27 ADR reported by diuretic users, and 15 were caused by furosemide users. 32 ADRs were endocrine damage. Causality assessment has been performed using the world health organization-Uppsala monitoring center, 63 possible followed by 13 probable/ likely. In the majority, 54 suspected ADRs were withdrawn. Based on the study duration, 40 were recovering stages. Monitoring and reporting of ADR among healthcare professionals should be encouraged as well as creating awareness of ADR reporting among patients can improve quality of life and prevent hospitalization.
S. Surekha and E. Bhavya *
Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, Tamil Nadu, India.
10 July 2020
02 December 2020
21 December 2021
01 January 2022