A REVIEW OF RECENT ADVANCES IN POLYMERIC SHAPE MEMORY HYDROGELAbstract
In Today’s world, there are many drug delivery systems available but there are many problems related to drug delivery systems like stability, degradation in-vivo. Drug delivery through tablets is the most convenient method due to patient compliance. Recently, hydrogels are hydrophilic 3-dimensional polymeric structures that have been explored by researchers due to their extraordinary promising potential in a wide range of applications such as drug delivery, sealing, and tissue engineering. These 3-D polymer networks with the ability of shape deformations show a volume phase transition. The polymers used in the formulation of hydrogel have low mechanical strength and difficult to handle. Shape memory hydrogels have been extensively explored and probed; however, no amalgamated information on their effective utilization in biomedical applications is available as such. In this review article, we systematically consolidate prevailing literature and briefly enumerate shape memory hydrogels based on their principles as well as their shape transitions in diverse environments, which significantly affects operational exploitations of shape memory hydrogels.
S. Kaur * and P. Gaba
Department of Pharmaceutics, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela, Punjab, India.
18 February 2020
08 May 2020
24 November 2020
01 December 2020