A REVIEW ON ANTIULCER ACTIVITYAbstract
Over the past decades, herbal medicine has become a thing of global significance with medicinal and economic implications. Wide spread use of herbs throughout the globe has raised serious concerns over its quality, safety, and efficacy. Our investigation showed that these investigated medicinal plants could prevent ulcer in a dose-dependent manner. Histological studies revealed that these medicinal plants did not show any acute toxicity. Preliminary photochemical screening of this medicinal plant identified the presence of important secondary metabolites like flavonoids and tannins. A peptic ulcer in the stomach is called a gastric ulcer. One that is in the duodenum is called a duodenal ulcer. Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of non-steroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause ulcers, but can make them worse. As many as 70-90% of ulcers are associated with Helicobacter pylori, a spiral-shaped bacterium that lives in the acidic environment of the stomach. Ulcers can also be caused or worsened by drugs such as aspirin and other NSAIDs. There has been considerable pharmacological investigation in to the antiulcer activity of some compounds. In this work, we have reviewed the literature on different medicinal plants for anti-ulcer activity, this article reviews the anti-peptic, gastro protective of the most commonly employed herbal medicines and their identified overall active constituents has been reported.
Pradip Kumar Maury*, S.K. Jain, Nand Lal and Shashi Alok
Department of Pharmacognosy, Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India
25 March, 2012
14 June, 2012
27 July, 2012
01 August, 2012