A REVIEW ON CLINICAL EFFICACY OF TRADITIONAL PLANTS ON OSTEOARTHRITISAbstract
Osteoarthritis is accepted as the most growing, frequent, debilitating and heterogeneous condition that worsens the quality of life globally in the elderly, affecting an estimated 10% of men and 18% of women over 60 years of age with a rise in both prevalence and incidence. At present, there is no definite cure for osteoarthritis and no effective treatments which arrest or slow its progression; however multiple numbers of treatments ranging from newly approved oral medications, topical agents, intra-articular injections to surgery exist, but these treatments are sometimes disappointing and may have a detrimental effect on health. Hence, traditional plants appear to be efficacious and safe with the anti-osteoarthritic effect that aid for greater relief of symptoms and/or disability along with highlighting various phytochemical with scientifically proven, and validated. In this present review study, an effort is made to treat OA by focusing on the clinical, scientific and mechanistic rationale for targeting inflammatory signaling pathways in OA by use of traditional plants.
S. K. Panda *, K. L. Kumari, L. Adhikari, P. K. Sahu and A. Pal
Olene Life Sciences Private Limited, Chennai, Tamil Nadu, India.
11 January 2019
08 July 2019
13 August 2019
01 September 2019