A REVIEW ON ETIOLOGY AND CHALLENGES ASSOCIATED WITH VARIOUS THERAPIES FOR THE TREATMENT OF PSORIASISAbstract
Psoriasis is autoimmune, hyperproliferative skin disease, which is affecting 2-5% of the population. Etiology of psoriasis is multi-factorial. The disease is identified as periodic recycle of events with red-scaly skin plaques. The epidemiology of Psoriasis is still unknown. From medication, this disease can only be prevented. Currently, there are many approaches to cure this disease, but still, no approach has completely cured the illness. New treatments are available for psoriasis, which are derived from biotechnology; they are known as biological drugs. The discovery of these new drugs derived from biotechnology prevents the activation of T-cells and targets cytokines. These drugs are less toxic and better functional, so patients, as well as a dermatologist, prefer the use of these biological drugs for the treatment of psoriasis over topical therapy, phototherapy, and systemic therapy. This review gives a detailed explanation of current therapies for the treatment of psoriasis and challenges associated along with it.
N. V. Gupta, K. Kowshik * and S. Kanna
Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagara, Mysuru, Karnataka, India.
03 February 2019
13 May 2019
14 June 2019
01 October 2019