A REVIEW ON HERBAL PLANTS SHOWING ANTIDEPRESSANT ACTIVITYAbstract
Depression is a heterogenous mood disorder that has been classified and treated in variety of ways. Although a number of synthetic drugs are being used as standard treatment for clinically depressed patient, they have adverse effects that can compromise the therapeutic treatment .Thus, it is worthwhile to look for antidepressant from plants with proven advantage and favorable benefit to risk ratio. A number of medicinal plants and medicine derived from these plants have shown antidepressant properties by virtue of combined effect of their medicinal constituents. The causes of depression are decreased brain levels of monoamines like noradrenaline, dopamine and serotonin. Therefore, drugs restoring the reduced levels of these monoamines in the brain either by inhibiting monoamine oxidase or by inhibiting reuptake of these neurotransmitters might be fruitful in the treatment of depression. The present review is focused on the medicinal plants and plants based formulations having antidepressant activity in animal studies and in humans.
Talha Jawaid*, Roli Gupta and Zohaib Ahmed Siddiqui
Hygia Institute of Pharmaceutical Education and Research, Lucknow, Uttar Pradesh, India
02 August, 2011
07 October, 2011
30 November, 2011
01 December, 2011