A REVIEW ON MECHANISTIC ASSESSMENT OF HEPATOTOXICITY AND MEDICINAL PLANTS WITH HEPATOPROTECTIVE POTENTIALAbstract
The liver is the most important organ in the body that plays a central role in the detoxification and excretion of many exogenous and endogenous compounds. Due to these functions, hepatic diseases continue to be among the main threats to public health, and that challenges health care professionals. Many liver diseases are chronic, meaning they last for years and may never go away. But even chronic liver diseases can usually be managed. The drugs that work on the liver are generally classified into two categories, one is antihepatotoxic agents, which generally antagonize the effects of any hepatotoxins causing any liver disease and another is hepatoprotective agents which prevent various types of liver infections prophylactically. Plants are the paramount source of herbal medicines. A plethora of data from the medicinal plants is available in literature. The present review is aimed at compiling data on promising herbs in concise manner, which are experimentally proved by the scientists as hepatoprotective.
Krishn Kumar Agrawal and Yogesh Murti *
Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India
08 June 2020
25 January 2021
21 May 2021
01 September 2021