A STUDY OF CARDIOVASCULAR AND ANTIMICROBIAL EFFECTS OF TINOSPORA CORDIFOLIA
AbstractTinospora cordifolia is known for a wide range of medicinal properties. In this study, cardiovascular and antimicrobial properties of aqueous and ethanolic extracts of Tinospora cordifolia were evaluated. Dose dependent negative ionotropic and chronotropic effects were observed with both aqueous and ethanolic extracts. The effects were antagonized by atropine indicating involvement of muscarinic receptors. Maximum antimicrobial activity was found with ethanolic extract of Tinospora cordifolia (15mm) against Pseudomonas aeruginosa. The organism showed resistance to aqueous extract giving an inhibition zone of 0.3mm. The data suggest that Tinospora cordifolia could be of benefit in arrhythmias and microbial infections.
Article Information
83
3486-3489
519KB
1047
English
IJPSR
J. Archana* and M.P. Kusuma
RBVRR Women’s college of pharmacy, Barkathpura, Hyderabad-500027, India
archana_jarc@yahoo.com
10 May, 2012
03 June, 2012
20 August, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3486-89
01 September, 2012
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