A STUDY OF CARDIOVASCULAR AND ANTIMICROBIAL EFFECTS OF TINOSPORA CORDIFOLIAAbstract
Tinospora cordifolia is known for a wide range of medicinal properties. In this study, cardiovascular and antimicrobial properties of aqueous and ethanolic extracts of Tinospora cordifolia were evaluated. Dose dependent negative ionotropic and chronotropic effects were observed with both aqueous and ethanolic extracts. The effects were antagonized by atropine indicating involvement of muscarinic receptors. Maximum antimicrobial activity was found with ethanolic extract of Tinospora cordifolia (15mm) against Pseudomonas aeruginosa. The organism showed resistance to aqueous extract giving an inhibition zone of 0.3mm. The data suggest that Tinospora cordifolia could be of benefit in arrhythmias and microbial infections.
J. Archana* and M.P. Kusuma
RBVRR Women’s college of pharmacy, Barkathpura, Hyderabad-500027, India
10 May, 2012
03 June, 2012
20 August, 2012
01 September, 2012