A STUDY ON PRELIMINARY PHYTOCHEMICAL AND DIURETIC ACTIVITY OF BARK OF THESPESIA POPULNEAAbstract
Thespesia populnea is a reputed ever green tree belonging to the family malvaceae; commonly known as Indian tulip tree. The plant is distributed tropical regions and coastal forest in India. It is well known and all the parts are used in traditional system of medicine. The plant has been used as astringent, antibacterial, hepatoprotective, haemostatic, anti-diarroheal and anti-inflammatory. The shade dried bark powder of Thespesia populnea was subjected to successive extraction using the solvents (Pet. ether, chloroform, alcohol and water). The diuretic potential of various extract of the barks was assessed in albino rats. The Volume of urine, urinary concentration of Na+, K+ and Cl– ions were the parameters of the study. Fursemide (100 mg/kg) was used as standard. The extract (400 mg/kg) has shown significant increase in the volume of urine, urinary concentration of Na+, K+ and Cl–. From the present study it may be concluded that the extract possess polyphenolic compounds, carbohydrates, proteins and possess natriuretic and diuretic activities.
R. PARTHASARATHY*, R. ILAVARASAN, RUPALI NANDANWAR
Bharath University, Selaiyur*, Chennai, India
07 January, 2010
25 January, 2010
29 January, 2010
01 February, 2010