A SYSTEMATIC REVIEW OF DIFFERENT ANALYTICAL METHODS FOR MAJOR PHYTOCONSTITUENTS OF TURMERIC AND BLACK PEPPERAbstract
Curcumin is a phytochemical isolated from Curcuma longa (Zingiberaceae) and has been used by ancient people for a long time to treat various ailments. Piperine is the main bioactive constituent that has been isolated from Piper nigrum L. Piperine increases the bioavailability of curcumin. Several analytical methods have been developed for the detection of curcumin and Piperine like high-Performance Liquid Chromatography (HPLC), high-performance thin layer chromatography (HPTLC), ultraviolet (UV) spectroscopic methods, Ultra-performance liquid chromatography (UPLC), and hyphenated methods. Numerous analytical techniques have been developed to quantify curcumin and piperine; most focus on accomplishing this separately. Only a few techniques have been created to determine curcumin and piperine in the combined dosage form simultaneously. The main purpose of this review is to describe a brief overview of the method development for Curcumin and Piperine in pharmaceutical dosage form, biological fluids, and Herbal formulations.
Selim Akhtar, Sadhana Sharma, N. R. Bhuyan, Bhupendra Shrestha and Vishala Rani Baraily *
Department of Pharmaceutical Analysis, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India.
08 July 2022
15 May 2023
20 May 2023
01 June 2023