ACCURACY OF STANDARDS IN CHOLESTROL DIAGNOSTIC KITS
AbstractThe percentage error observed in the claimed standard concentration of cholesterol 200 mg/dl for kits A to D is found to be 0.6, 12.3, 8.96 and 3.76 respectively. As per the guidelines of CLIA 8 allowable error is +10% for cholesterol estimation. Similarly as per the NCEP 9 guidelines + 9 % error is allowable. Therefore, it is noted that kit A is the best kit with an error of just 0.6% followed by kit D which showed an error of 3.76%. Kit C is the third best kit which had an error of 9%. However, kit B failed to meet the CLIA and NCEP requirements as it exhibited an error as high as 12.3%. This highlights that artificial standards provided by the kit manufacturers with reagents cannot be relied upon as a calibrator system, since at the very beginning of calibration the system would fail, as observed in case of kit B in this experiment.
Article Information
44
619-622
338KB
1073
English
IJPSR
Sunita Soni*, S.H. Ganatra and Ajay Soni
Adv V R Manohar Instt of DMLT, Hingana Road, Wanadongri, Nagpur-441 110, Maharashtra, India
s_sanjaysoni@rediffmail.com
02 September, 2013
26 October, 2013
04 January, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(2).619-22
01 February, 2014
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