ACUTE AND SUBACUTE TOXICITY STUDIES ON SHODHANA PROCESSED GUGGULAbstract
Ayurveda– The science of life is known to the mankind since time immemorial. It prolongs life span, maintains positive health and cures diseases. Due to its high effectiveness, popularity and the socio-economic status it was recognized as an independent branch of learning and has been known as “Rasa Shastra” and “Rasa chikitsa” in the field of Ayurveda. After the development of rasa Shastra it was made possible for the minerals and metals, precious and semiprecious stones to pass through various pharmaceutical processes like shodhana, Marana etc. for several times so as to convert these in to a form or compound which may suit to the human body and could be observed and assimilated easily into the system without exhibiting any toxic symptom. There are two objectives to purify a natural herb. There are two objectives of purification. First is to remove the external and internal impurities. The second reason is to increase the medicinal value. The shodhana processes of guggul can be done by general purification and specific purification. Present work involves study of hematological, biochemical, Histopathological changes in mice treated with Guggul before and after shodhana process.
Poonam Taru, Mukta Abhyankar*, Vaishali Undale and Ashok Bhosale
Seth Govind Raghunath College of Pharmacy, Saswad, Pune, Mahrashtra, India
05 October, 2012
29 December, 2012
29 January, 2013
01 February, 2013