ADVANCEMENTS IN SKIN DELIVERY: A TRANSDERMAL SCIENCEAbstract
Transdermal drug delivery system (TDDS) provides an alternate safe way of drug delivery compared to other invasive techniques. Documented advancement in transdermal science provides sustainable delivery of drug molecules, improved bioavailability, the better therapeutic efficacy of embedded drug’s and ability to deliver the drug at a constant rate and also reduces the adverse effects associated with oral delivery of drugs. Skin provides a formidable barrier for topical delivery of drugs to overcome its various agents have been used. TDDS have received more attention recently due to their unique features such as improve bioavailability, controlled release of medication and better patient compliance. Transdermal patches, which consist of the drug along with other ingredients provide an effective way to overcome this barrier. The present review mainly focuses on the various advancement of transdermal drug delivery, the various available method for preparation of transdermal patches, characterization and assessment tools for transdermal patch preparation, patents filled, clinical trial performed on transdermal compounds along with drug approved and future applications of transdermal drug delivery system.
K. Rajesh *, N. Upamanyu and V. Jain
School of Pharmacy and Research, Peoples University, Bhopal, Madhya Pradesh, India.
29 September 2019
30 December 2019
04 March 2020
01 July 2020