AN OVERVIEW ON MICROBIAL FIBRINOLYTIC PROTEASES
AbstractMicrobial fibrinolytic proteases are of considerable interest in view of their specific activity and stability at biological pH. This review describes different isolation methods which enable the screening and selection of promising organisms for industrial production. Further, strain improvement using mutagenesis and/or recombinant DNA technology can be applied to augment the efficiency of the producer strain to a commercial status. The various nutritional and environmental parameters affecting the production of fibrinolytic proteases are delineated. The purification and properties of these fibrinolytic proteases is discussed, and the use of fibrinolytic proteases is highlighted.
Article Information
2
643-656
378KB
1770
English
IJPSR
E. Venkata Naga Raju*and G. Divakar
Department of Biotechnology, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur - 522 510, Andhra Pradesh, India
Department of Biotechnology, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur - 522 510, Andhra Pradesh, India
15 September, 2013
21 November, 2013
16 February, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).643-56
01 March, 2014
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