AN OVERVIEW ON NANOEMULSION: A NOVEL APPROACHAbstract
The nanoemulsion is one of the most efficient dispersed nanosystems of droplet size ranging to submicron size. Nanoemulsions/ Sub-micron emulsions (SMEs)/ Mini-emulsions are thermodynamically stable transparent or translucent dispersions of oil and water stabilized by an interfacial film of surfactant and co surfactant molecules having a droplet size of less than 100 nm. This review provides brief information about method of preparation and evaluation of nanoemulsion as drug carriers for improving the delivery of therapeutic agents. several techniques are to be used for preparation of nanoemulsions like microfluidization, high pressure homogenization, low energy emulsification and solvent evaporation method and parameter that are to be used for its characterization like droplet size analysis, viscosity determination, drug content, refractive index, pH, zeta potential, Transmission electron microscopy, thermal stability, release and in vitro skin permeation study.
Ronak P. Patel* and Jay R. Joshi
Department of Pharmaceutics, A.R. College of Pharmacy and G.H. Patel Institute of Pharmacy, Motabazar, Vallabhvidhyanagar-388120, Gujarat, India
28 August, 2012
12 October, 2012
20 November, 2012
01 December, 2012