AN UNDERSTANDING OF PULSATING DRUG DELIVERY SYSTEM – A REVOLUTIONARY APPROACH IN PHARMACEUTICAL SCIENCEAbstract
Pulsatile drug delivery systems (PDDS) have attracted attraction because of their multiple release system. Pulsatile drug delivery systems are the new approach to overcome patient non-compliance over commercially used dosage forms. These techniques also help in treating the disorders based on circadian paradigm and the drugs are rapidly released according to the lag time decided by the carrier medium. This review covers different techniques of pulsatile drug delivery system and their marketed products. Biological rhythms play a pivot role in tolerance of any medicine given for the treatment of any disorder. This system enables the active drug for target action and inflated bioavailability with increased pharmacokinetics as well as pharmacodynamics profile of active moiety. The present review state diseases wherein pulsatile drug delivery systems are promising include asthma, peptic ulcers, cardiovascular ailments, arthritis and attention deficit syndrome in children and hypercholesterolemia. The author attracts attention of pulsatile drug delivery technique in Medical and for establishment in Pharmaceutical field simultaneously.
R. Taneja and G. D. Gupta *
Department of Pharmaceutical Research Div. ASBASJSM College of Pharmacy, Ropar, Punjab, India
25 August, 2015
21 December, 2015
30 December, 2015
01 February, 2016