ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF AQUA FORM OF CAESALPINIA BONDUCELLA SEED IN RATSAbstract
The objective of this study is to evaluate the analgesic and anti-inflammatory activities of the Caesalpinia bonducella in animals. The analgesic action was evaluated in rats using the acetic acid-induced writhing test and the hot-plate test. The anti-inflammatory activity was estimated using carrageenan-induced paw edema in rats. Caesalpinia bonducella strikingly and dose-dependently suppressed carrageenan-elicited paw edema in rats, inhibited the writhing response in rats, increased reaction time of in the hot-plate test. These findings propose that aqua of Caesalpinia bonducella seed has evident non-central analgesic and anti-inflammatory activities.
Md. Mahfoozurrahman, Hifzul Kabir*, M. Asif
Department of Ilmul Advia, Faculty of Medicine (U), Jamia Hamdard, New Delhi-62, India
03 July, 2012
21 September, 2012
28 October, 2012