ANALYTICAL METHODS OF TICAGRELOR: A REVIEWAbstract
Ticagrelor is a platelet aggregation inhibitor. It is used for the prevention of stroke, heart attack, and other events in people with the acute coronary syndrome, meaning problems with the blood supply in the coronary arteries. It acts as a platelet aggregation inhibitor by antagonising the P2Y 12 receptor. Its half-life is up to 12 h with the hepatic type of metabolism and biliary excretion. This review provides the pharmacokinetic and pharmacodynamics of the Ticagrelor, which also includes the review on pharmaceutical analytical techniques like High-performance liquid chromatography, Reverse phase – High-performance liquid chromatography, Bio-analytical techniques, UV spectrometry with the impurities, pharmaceutical dosage forms, bulk, and its formulations used for determination and validation. This review helps us to get updated information on validation of drug-Ticagrelor till current date.
G. Nikitha and A. Ajitha *
Department of Pharmaceutical Analysis, Faculty of Pharmaceutical Analysis, CMR College of Pharmacy, Medchal, Hyderabad, Telangana, India.
17 March 2021
12 June 2021
21 June 2021
01 December 2021