ANTI-ALLERGIC AND ANTICATALEPTIC ACTIVITY OF AQUEOUS EXTRACT OF LEAVES OF AILANTHUS EXCELSA ROXB.Abstract
The anti-allergic of an aqueous extract of the leaves of Ailanthus excelsa Roxb.(AELAq) was evaluated by using milk induced leucocytosis and eosinophilia in mice, passive paw anaphylaxis in rats models while the anticataleptic properties was evaluated by Clonidine induced catalepsy in mice mode. The extract significantly (*p<0.05, **p< 0.01) decreased the leucocytosis and eosinophilia along with passive paw anaphylaxis in the above experimental animals respectively. The extract also significantly (**p< 0.01) decreased Clonidine induced catalepsy in mice. These results suggest that aqueous extract AELAq may have the potential therapeutic value in the treatment of allergic diseases and to produce adaptogenic properties.
Dinesh Kumar *, Z A Bhat, P Singh, S C Mudgade, V D Bulani and S S Bhujbal
Department of Pharmaceutical sciences, University of Kashmir, Srinagar, India
14 May, 2010
19 August, 2010
26 August, 2010
01 September, 2010