ANTI BACTERIAL ACTIVITY OF 3- (4- ARYL SUBSTITUTED- 3 – YL) – THIAZOLIDIN- 4 – ONE AND THEIR DERIVATIVESAbstract
This study involves synthesis of 3- [4- aryl substituted- 3 – yl] – thiazolidin- 4 – one – 5- acetic acid by microwave oven induced synthesis method. Synthesized compounds were screened for anti-microbial activity by MIC and zone inhibition tests against various gram positive organism and gram negative organisms respectively. The microbiological assay is based upon a comparison of the inhibition of growth of micro-organism by measured concentration of the antibiotics to be examined with that produced by known concentration of a standard preparation of the antibiotic having a known activity.
M R Shivalingam *, D Jeslin, Y V Kishore Reddy, B Appa Rao, N Sunitha, Velpuri Amulya and T Jyothibasu
Department of Pharmaceutics, Victoria College of Pharmacy, Guntur, Andhra Pradesh, India
05 March, 2010
03 June, 2010
29 June, 2010
01 July, 2010