ANTI-DIABETIC ACTIVITY OF ROOTS OF QUERCUS INFECTORIA OLIVIER IN ALLOXAN INDUCED DIABETIC RATSAbstract
The methanolic extract of roots of Quercus infectoria Olivier at a dose of 250 mg/kg and 500 mg/kg body weight respectively was tested for anti-diabetic activity in Alloxan-induced hyperglycaemic rats. The blood glucose levels were measured at 0, 2h, 4h and 6h after the treatment. The methanolic extract reduced the blood glucose Alloxan- induced diabetic rats from 285.52 to 206.57mg/dl, 6h after oral administration of extract (P<0.01). The antidiabetic activity of methanolic extract of Quercus infectoria Olivierwas compared with glibenclamide, an oral hypoglycaemic agent (3mg/kg).
R. Saini * and S.M. Patil
Department of Pharmacy, Shree Dev Bhoomi Institute of Education, Science and Technology, Dehradun, Uttarakand, India
25 November, 2011
15 March, 2012
19 April, 2012
01 May, 2012