ANTI-DIARRHOEAL ACTIVITY OF METHANOLIC EXTRACT OF ROOT BARK OF AILANTHUS ALTISSIMA SWINGLE (FAMILY: SIMAROUBACEAE) ON EXPERIMENTAL ANIMALSAbstract
Ailanthus altissima Swingle (Simaroubaceae) is commonly known as “Tree of heaven”. The methanolic extract of root bark of A. altissima (MEA) was taken for anti-diarrhoeal activity. Investigations were carried out on castor oil induced diarrhoea and small intestine transit method on mice. In former method, MEA 200 (mg/Kg) were reducing the total weight of the faeces of group (0.163±0.028) in comparison to control group faeces (0.652±0.041), were statistically significant (P<0.001). In latter method, the MEA 200 (mg/Kg) inhibited 72.414% of the distance travelled by the charcoal and were significant statistically (P<0.001).
Munesh Mani*, Neetu Sachan, Ankita Tandon, Arun Kumar Wahi
College of Pharmacy, Institute of Foreign Trade and Management (IFTM), Moradabad (UP), India
29 July, 2010
24 October, 2010
09 November, 2010
01 December, 2010