ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF CYPERUS ROTUNDUS RHIZOME ON CARRAGEENAN INDUCED PAW EDEMA IN RATSAbstract
Cyperus rotundus Linn. (Cyperaceae) is an indigenous medicinal plant used for the treatment of pain, inflammation, diarrhoea, tumours, wounds and as Antidiabetic Anticonvulsant, Antimicrobial, Antiallergic, Antioxidant and Antiarthritic. The methanolic extract of rhizome was subjected to anti-inflammatory activity using experimental animal model of carrageenan induced paw edema in the presence of control for comparison. The results showed that methanolic extract significantly ameliorate oedema comparable to reference standard, Indomethacin. The results of this study explicate justification of the use of this plant in the treatment of inflammatory disease conditions.
Suneet Kumar*, Richa Tiwari and Niyaz Alam
Department of Pharmacy, Ram-Eesh Institute of Vocational and Technical Education, Knowledge Park-1, Kasna Road, Greator Noida, Gautambudh Nagar-201310, Uttar Pradesh, India
21 August, 2012
12 November, 2012
29 November, 2012
01 December, 2012