ANTI-INFLAMMATORY ACTIVITY OF SAMADERA INDICA LEAVES BY MEMBRANE STABILIZATIONAbstract
The present work aims at evaluating the anti-inflammatory activity of Samadera indica by HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. The anti-inflammatory activity of the crude ethanol extract, aqueous extract of leaves part of Samadera indica were compared to that of the standard drug diclofenac. The extract in concentration of 250-1000 µg/ml showed a dose dependent inhibition of haemolysis of erythrocyte induced by hypotonic solution. The ethanolic extract of Samadera indica showed significant anti-inflammatory activity in comparison to aqueous extract and with standard drug diclofenac.
G.R. Rajalakshmi* and Jyoti Harindran
Research Scholar, Karpagam University, Karpagam, Coimbatore, Tamil Nadu-641021, India
20 October, 2012
24 November, 2012
25 January, 2013
01 February, 2013