ANTI-INFLAMMATORY ACTIVITY OF THE AERIAL PARTS EXTACTS OF CAESALPINIA MIMOSOIDES LAMKAbstract
Caesalpinia mimosoides Lamk. is a prickly climbing shrub belongs to Leguminosae family. various parts of this plant have been used in the treatment of ulcer, inflammation, wound healing and arthritis. The present study aimed at the evaluation of anti inflammatory property of different extracts of aerial parts by in vitro and in vivo methods. In vitro methods were estimated by protein denaturation and proteinase inhibition method. An in vivo method was estimated on the carragenan paw edema. Acute toxicity studies were performed as per OECD-423 guidelines. Toxicity signs and symptoms were not observed. Both methods showed significant anti-inflammatory activity of the different extracts tested.
V. V. Lakshmi * and S. P. Bobby
Department of Pharmaceutical Chemistry, University College of Pharmacy, MG University, Cheruvandoor campus, Kottayam, Kerala, India
16 May, 2015
11 July, 2015
30 September, 2015
01 December, 2015