ANTI-INFLAMMATORY ACTIVITY OF WHOLE PLANT OF BELOPERONE PLUMBAGINIFOLIA (ACANTHACEAE)Abstract
In the present study anti-inflammatory activity of ethanol extract of Beloperone plumbaginifolia whole plant were investigated. The anti-inflammatory activity of ethanol extract of whole plant of B.plumbaginifolia were evaluated by carageenan induced rat paw edema to determine its effect on acute phase of inflammation models in rats. The phytochemical screening of ethanol extract of whole plant of B. plumbaginifolia revealed the presence of alkaloid, catechin, coumarin, flavonoid, phenol, tannin, saponin, steroid, glycoside and terpenoid. Maximum inhibition (78.63%) was obtained at the dose of 400 mg/kg of B.plumbaginifolia whole plant after 3h of treatment in carrageenen induced paw edema, whereas indomethacin produced 77.34% of inhibition. The present study suggested that B.plumbaginifolia whole plant extract possess strong anti-inflammatory property.
G. Sathiyabalan, R. M. Evanjaline, S. Muthukumarasamy and V. R. Mohan*
Ethnopharmacology Unit, Research Department of Botany, V.O. Chidambaram College, Tuticorin, Tamil Nadu, India.
09 May, 2017
14 July, 2017
25 July, 2017
01 January, 2018