ANTI-INFLAMMATORY ACTIVITY POTENTIAL OF ARECA CATECHU LEAF EXTRACTS-AN IN-VITRO STUDYAbstract
Areca catechu L. (Arecaceae) is a species of palm mainly grown in Asian countries for seed crop. Areca nut leaves are commonly used in traditional systems of medicine against various ailments. There is a need for identifying native natural plant sources to acquire their recognized medicinal properties, which may widen them to use as new therapeutics for various diseases. Phytochemical investigation of the leaves of Areca catechu L. yielded a alkaloid- Arecoline, from the chloroform extract; a flavonoid- Apigenin, from the methanol extract and a steroid- Stigmasterol, from petroleum ether extract. In-vitro methods were used to evaluate the pharmacological activity of the leaves of Areca catechu L. Anti-inflammatory activity of the leaves of Areca catechu was estimated by using standard methods like protein denaturation method using bovine serum albumin fraction and egg albumin and by HRBC membrane stabilization method. The result suggests that the leaves possess good antioxidant as well as anti-inflammatory activity.
N. G. D’ Souza, J. Fernandes * and S. D’ Souza
Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Paneer, Deralakatte, Mangalore, Karnataka, India.
12 October 2020
22 February 2021
24 May 2021
01 September 2021