ANTI-PSORIATIC ACTIVITY AND HPTLC FINGERPRINTING OF PREPARED POLY-HERBAL CREAM

The current investigation’s goal is to prepare polyherbal cream by using plant extracts of Terminalia chebula, Sapindus trifoliatus, Psoralea corylifolia and carry out high-performance thin layer chromatography fingerprinting to confirm that the corresponding extracts utilized as standards contain the active ingredients. Cream of plant extract prepared by using fusion method and the prepared cream formulation was examined qualitatively in order to determine whether any active phytoconstituents were present and its anti-psoriatic activity. Thus, high-performance thin layer chromatography fingerprinting emerged as crucial instrument for identification, subjective analysis, a phytochemical evaluation of polyherbal cream of Terminalia chebula, Sapindus trifoliatus, Psoralea corylifolia seed extracts. Prepared polyherbal cream characterised by different parameters including irritancy test, wash ability test, phase separation and spreadability. The present study concluded that the High-performance thin layer chromatography studies showed presence of β-sitosterol and psoralen in prepared polyherbal cream. Prepared herbal cream showed the most promising anti-psoriatic effect. Active constituents responsible for treating psoriasis were present in the obtained polyherbal extract.