ANTIBACTERIAL AND PHYTOCHEMICAL EVALUATION OF THREE MEDICINAL PLANTS OF BANGLADESHAbstract
The present study was carried out to illustrate the relative evaluation of phytochemical constituents and antimicrobial activity of leaves of Eclipta alba and Aphanamixis polystachya and bark of Premna integrifolia in two different solvents. A preliminary phytochemical analysis was done and concluded that the presence of alkaloids, tannins, flavonoids and glycoside in both extracts of the above plants. The antimicrobial activity was tested using disc diffusion method against eight pathogenic bacteria using Kanamycin as antibiotic standards. The outcome showed that the antibacterial activity was effective in chloroform and ethyl acetate fractions of tested extracts. The MIC was determined in two different solvents of both extracts and observed that chloroform and ethyl acetate possess minimum inhibition in both extracts. From the current investigation, it can be concluded that Eclipta alba, Aphanamixis polystachya and Premna integrifolia crudeextracts have quite effective antimicrobial activity and potent phytochemical constituents.
Farhana Alam Ripa*, Laizuman Nahar , Abul Fazal and Mst. Hajera Khatun
Senior Lecturer, Department of Pharmacy, Southeast University, Banani, Dhaka-1213, Bangladesh
25 October, 2011
23 February, 2012
25 February, 2012