ANTIBIOGRAM ASSESSMENT AGAINST UPPER RESPIRATORY TRACT INFECTION CAUSING BACTERIAAbstract
Human body is a perfect natural habitat for numerous microorganisms like bacteria, fungi, yeasts and some viruses which are termed as microflora of a body. Amongst its upper respiratory tract, is the most common infections in the world. Our study aimed at determining the antimicrobial resistance of bacterial strains against several antibiotics, isolated from the respiratory tract of the suspected patients. The study was confirmed using in vitro antimicrobial disk diffusion method. Total of 30 samples were studied. 20 bacterial strains were isolated of which 15 were Gram positive bacteria, including Staphylococcus aureus (7 strains), Staphylococcus epidermidis (4 strains) and Corynebacterium diphtheria (4 strains) whereas 5 strains of Gram negative bacteria, includes Neisseria meningitidis. The resistance determined by the antibiotics used as, amoxicillin, Staphylococcus aureus (87.71%), Staphylococcus epidermis (85.71%), Corynebacterium diphtheria (75%), erythromycin, Staphylococcus epidermidis (100%), Corynebacterium diphtheria (100%), Neisseria meningitidis (60%), Staphylococcus aureus (57.14%); tetracyclin, Staphylococcus epidermidis (50%), Corynebacterium diphtheria (50%), Neisseria meningitidis (40%), Staphylococcus aureus (29%); ciprofloxacin, Neisseria meningitidis (80%), Staphylococcus aureus (29%); penicillin showed 100 % resistance towards all the isolates. The susceptibility of S. aureus was highest among all the isolates. Among the antibiotics Penicillin had the highest resistance. Most of the isolates were multi-drug resistance towards various antibiotics. The ability of the antibiotics to inhibit the growth of bacterial isolates indicated that they are effective antimicrobial agents in upper respiratory tract infections.
Mayuri Khare, Nishi Yadav, Rakesh Kumar Patidar, Swati Bagde and Vinod Singh*
Department of Microbiology, Barkatullah University, Bhopal, Madhya Pradesh, India
15 August, 2012
14 September, 2012
24 December, 2012
01 December, 2012