ANTIFERTILITY INVESTIGATIONS ON THE ETHANOL EXTRACT OF EUGENIA SINGAMPATTIANA BEDD LEAF IN MALE ALBINO RATSAbstract
Antifertility effect of ethanol extract of leaf of Eugenia singampattiana was observed in male albino rats. The relative weight of the testes and epididymis were decreased. The epididymal sperm count, motility and sperm abnormality were reduced significantly in treated rats. There was an increase in serum urea, creatinine and the activity of liver marker enzyme (SGOT) levels of drug treated rats. The results of the hormonal assay showed increased serum levels of FSH and estrogen but decreased levels of LH and testosterone when compared to control. The results of the present study concluded that, ethanol extract of leaf of E. singampattiana inhibited sperm concentration, motility and testosterone which might result in a male fertility.
S. Mary Jelastin Kala, P.S. Tresina and V.R. Mohan*
Ethnopharmacology Unit, Research Department of Botany , V.O. Chidambaram College, Tuticorin-628008, Tamil Nadu, India
22 January, 2014
03 March, 2014
05 April, 2014
01 July, 2014