ANTIMICROBIAL EFFICACY OF METHANOLIC EXTRACT OF WHOLE PLANT OF NELUMBO NUCIFERA GAERTN.Abstract
The aim of the present investigation was to evaluate the antimicrobial efficacy of methanolic extract of whole plant of Nelumbo nucifera Gaertn. The methanolic extract of Nelumbo nucifera were tested for antibacterial efficacy against three gram positive bacteria & three gram negative bacteria and antifungal activity against three fungal strains by disc diffusion method. In present study Ciprofloxacin 100 mcg/ml (antibacterial) and Ketakonazole 100 mcg/ml (antifungal) used as a reference standard. The methanolic extract of Nelumbo nucifera at the concentration of 150mcg/ml were found significant antimicrobial activity against the entire organism was tested. This study scientifically supports the usage of whole plant as a remedy for various superficial bacterial and fungal infections in traditional medicine.
M. Sakthi Abirami , R. Nandini , D. Satheesh Kumar*, R. Indhumathy and G. Saikala Devi
M.Pharm, (Ph.D), Department of Pharmacy, Annamalai University, Annamalai Nagar, Cuddalore, Tamil Nadu, India
15 November, 2010
27 January, 2011
17 February, 2011
01 March, 2011