ANTIOXIDANT AND ANTICANCER THERAPEUTIC POTENTIALITY OF MUSHROOMS: A REVIEWAbstract
Cancer is a substantial world health threat, & a largest cause of death in peoples of various age groups and economic backgrounds. This dramatic increase in the global burden of cancer has spurred research and many pharmacological studies as an attempt to limit the progression of this disease. Painful, expensive chemotherapy by dietary supplements have come forth as a novel significant approach in ailment of cancer. Since ancient times mushrooms has been used a good resource of dietary supplement. Mushroom is attributed by many medicinal properties, due to presence of phytochemicals, antioxidant, anticancer, antiviral, antimicrobial, anti-diabetic, anti-inflammatory etc. bioactive compounds in fruiting bodies and cultured mycelium. Polysaccharides and antioxidant have been extensively studied biologically active compounds of mushroom for their cytotoxic as well as immunomodulation properties. In this review we will highlight the recent findings on anticancereous bioactive compounds of mushroom, their therapeutic potentials and mode of action and the need for further investigation in cancer management.
Arvind K. Sharma , Madhu Gupta , Archana Shrivastav and A.M. Jana*
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11 March, 2013
21 July, 2013
28 September, 2013
01 October, 2013