ANTIPYRETIC ACTIVITY OF THESPESIA POPULNEA FRUITSAbstract
In the present study, the alcoholic and aqueous extracts of Thespesia populnea were investigated for their antipyretic activity. Suspension of subcutaneous administration of brewer’s yeast in albino rat leads to pyrexia. Oral administration of extracts at a dose of 500 mg/kg body weight significantly reduced the elevated body temperature of rat. This antipyretic effect has been compared with antipyretic effect of standard paracetamol.
E. N. Siju *, G. R.Rajalakshmi , Arun Shirwaikar
Assistant Professor and Head, Department of Pharmacology, Academy of Pharmaceutical Science, Pariyaram Medical College, Kannur, 670503, Tamil Nadu, India
18 October, 2013
14 November, 2013
26 February, 2014