ASSESSING THE ANTIOXIDANT ACTIVITIES OF METHANOLIC EXTRACT OF SARACA ASOCA LEAVES AND BARKAbstract
Chronic diseases such as cardiovascular, cancer, and respiratory diseases are being increased. Reactive oxygen species, free radicals, and oxidative stress play a major role in aggravating these diseases. Plants and plant-derived compounds have shown a greater potential in combating the detrimental effects of free radicals and other toxic agents. The current research work has been done on the leaf and bark of Saraca asoca to evaluate its free radical scavenging antioxidant properties. The antioxidant activities of Saraca asoca methanolic extract were assessed by employing ABTS Radical Scavenging Capacity, DPPH, Superoxide Radical, Hydroxyl Radical, Lipid Peroxidation, and Nitric Oxide Scavenging Ability. The leaf and bark extract results assessed against ARSC, DPPH, Superoxide, Hydroxyl, Lipid Peroxidation, Nitric Oxide, FRAP exhibited remarkable IC50 values in a concentration-dependent manner, thus proving it as a potential antioxidant. The results of the present comprehensive analysis demonstrated that Saraca asoca leaf and bark extract exhibited excellent antioxidant activities and could be exploited for further nutraceutical and medicinal applications effective in treating many disorders.
Sonal Prasad, Tabish Qidwai * and Rohit Saluja
Faculty of Biotechnology, IBST, Shri Ramswaroop Memorial University, Lucknow, Barabanki- Uttar Pradesh, India.
14 March 2022
17 July 2022
09 September 2022
01 November 2022