AUTHENTICATION OF MORPHOLOGICALLY SIMILAR RHIZOME DRUGS BASED ON TLC FINGERPRINT PROFILES AND VALERENIC ACID CONTENT
AbstractObjective: Present study involved comparison of thin layer chromatograms and quantification of valerenic acid (VA) in four morphologically similar rhizome drugs – Valeriana jatamansi, Nordostachys jatamansi, Selinum vaginatum and Ferula sumbul. Materials and methods: Ethanol extract of the four drugs were prepared under standard conditions and VA content was determined using TLC densitometry. Results: Comparative fingerprint chromatograms of the four drugs were developed and mean content of VA was calculated. S. vaginatum contains maximum VA content (360.22 µg/g). Conclusion: The four closely allied drugs could easily be differentiated based on thin layer chromatograms and VA content
Article Information
30
3428-31
305
1407
English
IJPSR
Sonali Batra, Ashwani Kumar* and Anupam Sharma
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
bashwani@pu.ac.in
04 March, 2016
07 May, 2016
31 May, 2016
10.13040/IJPSR.0975-8232.7(8).3428-31
01 August 2016
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