BIO EFFICACY OF MICHELIA CHAMPACA LINN ON MEMBRANE BOUND ENZYMES IN CCl4 INDUCED HEPATOTOXICITY IN RATS
AbstractThe aim of the present study is to evaluate the protective effect of flower extract of Michelia champaca on membrane bound enzyme (serum ATPase) levels on male albino rats. The membrane bound enzymes (Ca2+ ATPase, Mg2+ ATPase, Na+K+ ATPase) levels of methanolic flower extract of Michelia champaca at a dose of 300 mg/kg was evaluated during exposure to CCl4. There was a significant decrease in membrane bound enzymes such as Ca2+ ATPase, Mg2+ ATPase, Na+K+ ATPase was observed in CCl4 treated rats. Therapeutic treatment with plant extract has significantly ameliorated to near normalcy in the curative group. These results of the study concluded that Michelia champaca was found to be effective in preventing the biochemical abnormalities caused by toxins
Article Information
41
4879-81
285
1105
English
IJPSR
T. Ananthi* and R. Anuradha
PG and Research Department of Biochemistry, S.T.E.T Women’s College, Sundarakkottai, Mannargudi, Tamil Nadu, India
elangani576@gmail.com
01May, 2015
24 August, 2015
24 October, 2015
10.13040/IJPSR.0975-8232.6(11).4879-81
01 November, 2015