BIOLOGICAL ACTIVITY EVALUATION OF NOVEL N-HETEROCYCLIC CARBENE PRECURSORSAbstract
Five novel benzimidazolium salts were synthesized as N-heterocyclic carbene (NHC) precursors (1a–e). They were characterized by different techniques. The antimicrobial activities of these compounds were tested. The compounds showed moderate activity against three Gram (+) and seven Gram (-) bacteria in comparison to tetracycline, which was used as the standard antibiotic, whereas all the compounds (1a-e) showed no activity against the test yeast C. albicans.
Senem Akkoç *, Yetkin Gök, Hülya Erdoğan and Sevil Albayrak
Department of Chemistry, Faculty of Sciences, Erciyes University, Kayseri, Turkey
15 July, 2016
12 September, 2016
04 November, 2016
01 January, 2017