CHANGES IN WBC DIFFERENTIAL COUNT PATTERN IN MALE ALBINO RATS TREATED WITH GARLIC (ALLIUM SATIVUM) EXTRACTAbstract
The prophylactic efficacy of garlic (Allium sativum Linn.) (Alliaceae) extract was studied on changes in WBC differential count pattern in male albino rats. The rats were divided into four groups A, B, C and D, keeping group A as a healthy control. The garlic extract was tried in three different doses, 1ml, 2ml and 4ml/ kg body weight as low, medium and high dose respectively and given orally for the period of 7, 14, 21 or 28 days daily to the rats of group B, C and D as stated above. The results clearly indicate that a significant increase (P<0.01) in lymphocyte and eosinophil percent and a significant decrease (P<0.01) in neutrophil and monocyte percent at low and medium dose but at higher dose their percentage increases within the normal values. This investigation indicates not only the benefits and drawback of raw garlic but also its uses in regulation of certain parameters for well-being of individuals.
Sashank Srivastava and P. H. Pathak*
Department of Zoology, D.D.U. Gorakhpur University, Gorakhpur – 273 009, Uttar Pradesh, India
16 February, 2012
11 May, 2012
22 May, 2012
01 June, 2012