CHARACTERIZATION AND IDENTIFICATION OF ACTIVE COMPOUND OF OCELLATED SNAKEHEAD (CHANNA PLEUROPHTHALMUS BLKR) WASTE CHARCOAL POTENTIAL AS ANTIALLERGY DRUGAbstract
Natural resources potentials, such as animals or plants, have been utilized as a traditional herb and can be benefitted for human health and to support the government program in medication to be back to nature. The body parts often used for the traditional drug are meat, horn, tail, feather, nail, fat, bile, and shell. The animal’s potential to develop as medicine meets the following criteria: easily found, available in high numbers, and able to cure severe disease, and has economic value. In Central Kalimantan, one of the allergy treatment hereditarily practiced is the utilization of charcoal of inedible body parts of ocellated snakehead Channa pleurophthalmus Blkr, such as head skin, scale, and fins. This study was carried out to know the charcoal characteristics of ocellated snakehead (Channa pleurophthalmus Blkr) body parts in relation to its potential as an anti-allergic drug. The examination covered chemical composition, water content, rendement, charchoal absorbability, in-vivo test on a male rat, and pyrolysis-GC/MS (Py-GC/MS)-based active compound identification. Results showed that the charcoal was dominated by 55.547%-67.744% carbon. The lowest water content, 1.614%, the highest rendement, 3.7612%, and the highest absorbability, 757.14 mg/g, were recorded in the caudal fin. The Py-GC/MS analysis found the active compound of Hexadecanenitrile in the caudal fin charcoal. This compound is believed to be an anti-allergy.
Aryani *, E. Suprayitno, B. B. Sasmito and Hardoko
Faculty of Fisheries and Marine Science, Brawijaya University, Malang, East Java, Indonesia.
11 February 2020
11 May 2020
20 May 2020
01 February 2021